Ezio Fok

Ezio is a final year Phd student from the gene expression and biophysics laboratory under the supervision of Prof Musa Mhlanga. He is currently based at the CSIR. He has a keen interest in developing synthetic biology tools to answer fundamental questions in biology, having previously worked on building bacterial sensors using riboswitches and optimising CRISPR/Cas9 gene editing strategies in mammalian cells. Currently, for his phd, he works on studying the role of long non-coding RNAs and nuclear architecture in the transcriptional regulation of immune genes. Some of his work was recently published in Nature Genetics, where he was part of a team that unraveled the molecular mechanism that underlies the phenomenon of trained immunity.